Cavero, Icilio G.: search on Z-Library

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1

Human organotypic bioconstructs from organ-on-chip devices for human-predictive biological insights on drug candidates

Cavero, Icilio, Guillon, Jean-Michel, Holzgrefe, Henry H

Journal:

Expert Opinion on Drug Safety

Year:

2019

Language:

english

File:

PDF, 2.26 MB

english, 2019

2

The development of glutamate-based antidepressants is taking longer than expected

Garay, Ricardo, Zarate, Carlos A., Cavero, Icilio, Kim, Yong-Ku, Charpeaud, Thomas, Skolnick, Phil

Journal:

Drug Discovery Today

Year:

2018

Language:

english

File:

PDF, 628 KB

english, 2018

3

Safety Pharmacology assessment of drugs with biased 5-HT2B receptor agonism mediating cardiac valvulopathy

Cavero, Icilio, Guillon, Jean-Michel

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2014

Language:

english

File:

PDF, 748 KB

english, 2014

4

ICH S7B draft guideline on the non-clinical strategy for testing delayed cardiac repolarisation risk of drugs: a critical analysis

Cavero, Icilio, Crumb, William

Journal:

Expert Opinion on Drug Safety

Year:

2005

Language:

english

File:

PDF, 231 KB

english, 2005

5

Influence of plasma protein content and platelet number on the potency of PAF and its antagonist RP 59227 in rabbit platelet preparations

Anne Floch, Icilio Cavero

Journal:

British Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 950 KB

english, 1990

6

Increase in Plasma Renin Activity Evoked by Fenoldopam in Dogs is Directly Mediated by Dopamine1 Receptor Stimulation

Montier, François, Katchadourian, Philippe, Pratz, Jean, Cavero, Icilio

Journal:

Journal of Cardiovascular Pharmacology

Year:

1989

File:

PDF, 4.19 MB

1989

7

Ischemic myocardial cell protection conferred by the opening of ATP-sensitive potassium channels

Icilio Cavero, Yasmine Djellas, Jean-Michel Guillon

Journal:

Cardiovascular Drugs and Therapy

Year:

1995

Language:

english

File:

PDF, 1.20 MB

english, 1995

8

QT interval prolongation by non-cardiovascular drugs: issues and solutions for novel drug development

William Crumb, Icilio Cavero

Journal:

Pharmaceutical Science & Technology Today

Year:

1999

Language:

english

File:

PDF, 293 KB

english, 1999

9

Cross tachyphylaxis to endothelin isopeptide-induced hypotension: a phenomenon not seen with proendothelin

Anne-Charlotte Le Monnier de Gouville, Icilio Cavero

Journal:

British Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 1.50 MB

english, 1991

10

Peripheral dopamine receptors, potential targets for a new class of antihypertensive agents: Part I: Subclassification and functional description

Icilio Cavero, Roy Massingham, Françoise Lefèvre-Borg

Journal:

Year:

1982

Language:

english

File:

PDF, 529 KB

english, 1982

11

The use of electrocardiograms in clinical trials: a public discussion of the proposed ICH E14 regulatory guidance

Cavero, Icilio, Crumb, William

Journal:

Expert Opinion on Drug Safety

Year:

2005

Language:

english

File:

PDF, 91 KB

english, 2005

12

Safety Pharmacology Society: 7th Annual Meeting

Journal:

Expert Opinion on Drug Safety

Year:

2008

Language:

english

File:

PDF, 173 KB

english, 2008

13

Studies on the Mechanisms of the Development of Tolerance to the Hypotensive Effects of Fenoldopam in Rats

Lefèvre-Borg, Françoise, Lorrain, Janine, Lechaire, Jacqueline, Thiry, Chantal, Hicks, Peter E., Cavero, Icilio

Journal:

Journal of Cardiovascular Pharmacology

Year:

1988

File:

PDF, 6.70 MB

1988

14

Parasympatholytic activity of (-)-Δ9-trans- Tetrahydrocannabinol in mongrel dogs

Icilio Cavero, Joseph P. Buckley, Bhagavan S. Jandhyala

Journal:

European Journal of Pharmacology

Year:

1972

Language:

english

File:

PDF, 214 KB

english, 1972

15

Paf binding sites: Characterization by [3h]52770 rp, a pyrrolo[1,2-c]thiazole derivative, in rabbit platelets

Christine Robaut, Gabrielle Durand, Claude James, Daniel Lave, Pierre Sedivy, Anne Floch, Serge Mondot, Daniel Pacot, Icilio Cavero, Gérard Le Fur

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 1017 KB

english, 1987

16

Trophoblastic localization of [125I] endothelin-1binding sites in human placenta

André Malassiné, Françoise Mondon, Christine Robaut, Micheline Vial, Josette Bandet, Gisèle Tanguy, William Rostène, Icilio Cavero, Françoise Ferré

Journal:

Year:

1993

Language:

english

File:

PDF, 2.93 MB

english, 1993

17

Studies on the mechanism of the vasodilator effects of prazosin in dogs and rabbits

Icilio Cavero, Simone Fenard, Roberto Gomeni, Françoise Lefevre, Alan G. Roach

Journal:

European Journal of Pharmacology

Year:

1978

Language:

english

File:

PDF, 936 KB

english, 1978

18

Promises and partnership: FDA's Critical Path Initiative and its intersection with pharmacology: an ASPET 2011 annual meeting symposium

Journal:

Expert Opinion on Drug Safety

Year:

2011

Language:

english

File:

PDF, 280 KB

english, 2011

19

A Differential Effect of Chronically Administered Guanethidine on Sympathetic Neurotransmission to the Dog Heart and Mesenteric Arterial Blood Vessels

Clarke, David E., Jandhyala, Bhagavan S., Cavero, Icilio, Dixit, Balwant N., Buckley, Joseph P.

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

1974

Language:

english

File:

PDF, 679 KB

english, 1974

20

Drugs that prolong QT interval as an unwanted effect: assessing their likelihood of inducing hazardous cardiac dysrhythmias

Cavero, Icilio, Mestre, Michel, Guillon, Jean-Michel, Crumb, William

Journal:

Expert Opinion on Pharmacotherapy

Year:

2000

Language:

english

File:

PDF, 603 KB

english, 2000

21

Nicorandil Attenuates Myocardial Dysfunction Associated with Transient Ischemia by Opening ATP-Dependent Potassium Channels

Auchampach, John A., Cavero, Icilio, Gross, Garrett J.

Journal:

Journal of Cardiovascular Pharmacology

Year:

1992

File:

PDF, 578 KB

1992

22

Time-dependent fading of the activation of KATP channels, induced by aprikalim and nucleotides, in excised membrane patches from cardiac myocytes

Dominique Thuringer, Icilio Cavero, Edouard Coraboeuf

Journal:

British Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.92 MB

english, 1995

23

The blood pressure lowering effects of intravenous versus intracerebroventricular prazosin in anaesthetised cats

Alan G. Roach, Roberto Gomeni, Mervyn Mitchard, Jean-Paul Nicolas, Icilio Cavero

Journal:

European Journal of Pharmacology

Year:

1978

Language:

english

File:

PDF, 628 KB

english, 1978

24

Drug discovery paradigms: past, present, future – a centennial symposium of the American Society for Pharmacology and Experimental Therapeutics

Cavero, Icilio, Kaplan, Harvey R

Journal:

Expert Opinion on Drug Discovery

Year:

2008

Language:

english

File:

PDF, 251 KB

english, 2008

25

Endothelin-1 Binding Sites and Immunoreactivity in the Cultured Human Placental Trophoblast: Evidence for an Autocrine and Paracrine Role for Endothelin-1

Ferré, Françoise, Mondon, Françoise, Mignot, Thérèse-Marie, Cronier, Laurent, Cavero, Icilio, Rostene, William, Malassine, André

Journal:

Journal of Cardiovascular Pharmacology

Year:

1993

File:

PDF, 3.04 MB

1993

26

Effects of Prazosin on Reflex Changes in Heart Rate Evoked by Vasopressor and Vasodepressor Stimuli in Conscious Rabbits

Journal:

Journal of Cardiovascular Pharmacology

Year:

1982

File:

PDF, 334 KB

1982

27

Stimulation of Peripheral Dopamine Receptors in Rats: A Mechanism for Novel Antihypertensive Agents

Lefegvre-Borg, Francloise, Cavero, Icilio

Journal:

Clinical Science

Year:

1980

Language:

english

File:

PDF, 305 KB

english, 1980

28

Validation of a novel technique allowing assessment of the functional role of cardiac prejunctional receptors in the rat

Icilio Cavero, Chantal Thiry

Journal:

Autonomic and Autacoid Pharmacology

Year:

1990

Language:

english

File:

PDF, 612 KB

english, 1990

29

Analysis of the nonclinical telemetered ECG: Impact of logging rate and RR bin width in the dog and cynomolgus monkey

Henry H. Holzgrefe, Icilio Cavero, Carol R. Gleason

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2007

Language:

english

File:

PDF, 365 KB

english, 2007

30

The Myocardial Lesions Produced by the Potassium Channel Opener Aprikalim in Monkeys and Rats Are Prevented by Blockade of Cardiac β-Adrenoceptors

Vincent Belin, Thomas Hodge, Philippe Picaut, Roy Jordan, Carol Algate, Sylvie Gosselin, Gerhard Nohynek, Icilio Cavero

Journal:

Fundamental and Applied Toxicology

Year:

1996

Language:

english

File:

PDF, 2.19 MB

english, 1996

31

The effect of (−)-Δ9-trans-tetrahydrocannabinol on myocardial contractility and venous return in anesthetized dogs

Icilio Cavero, Mustafa F. Lokhandwala, Joseph P. Buckley, Bhagavan S. Jandhyala

Journal:

European Journal of Pharmacology

Year:

1974

Language:

english

File:

PDF, 623 KB

english, 1974

32

Time-course effects of oral guanethidine administration on cardiovascular and autonomic effects on dogs

Bhagavan S. Jandhyala, Icilio Cavero, Joseph P. Buckley

Journal:

European Journal of Pharmacology

Year:

1976

Language:

english

File:

PDF, 892 KB

english, 1976

33

Evidence for NK-1 receptor subtypes from in vivo bronchopulmonary and cardiovascular studies

Anne Floch, Nicole Massa, Chantal Thiry, Icilio Cavero

Journal:

Regulatory Peptides

Year:

1993

Language:

english

File:

PDF, 116 KB

english, 1993

34

K+ channel openers and ‘natural’ cardioprotection

Denis Escande, Icilio Cavero

Journal:

Trends in Pharmacological Sciences

Year:

1992

Language:

english

File:

PDF, 561 KB

english, 1992

35

Optimizing the preclinical/clinical interface: an Informa Life Sciences conference

Journal:

Expert Opinion on Drug Safety

Year:

2007

Language:

english

File:

PDF, 315 KB

english, 2007

36

Inhibition of central pressor effects of angiotensin I and II

Thomas A. Solomon, Icilio Cavero, Joseph P. Buckley

Journal:

Journal of Pharmaceutical Sciences

Year:

1974

Language:

english

File:

PDF, 459 KB

english, 1974

37

Safety pharmacology and prolongation of the QT interval

Icilio Cavero, Gan-Xin Yan, Robert Lux, Uwe Steinhoff

Journal:

Journal of Electrocardiology

Year:

2007

Language:

english

File:

PDF, 112 KB

english, 2007

38

Avoiding adverse modification of cardiac repolarization

Icilio Cavero, Rob Towart

Journal:

Pharmaceutical Science & Technology Today

Year:

2000

Language:

english

File:

PDF, 43 KB

english, 2000

39

14th Annual Meeting of the Safety Pharmacology Society: threading through scientific sessions for originality and novelty

Journal:

Expert Opinion on Drug Safety

Year:

2015

Language:

english

File:

PDF, 477 KB

english, 2015

40

Novel probabilistic method for precisely correcting the QT interval for heart rate in telemetered dogs and cynomolgus monkeys

Henry H. Holzgrefe, Icilio Cavero, Carol R. Gleason, William A. Warner, Lewis V. Buchanan, Michael W. Gill, Dennis E. Burkett, Stephen K. Durham

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2007

Language:

english

File:

PDF, 667 KB

english, 2007

41

Effects of β2-adrenoceptor agonists on anti-IgE-induced contraction and smooth muscle reactivity in human airways

Isabelle Gorenne, Carlos Labat, Xavier Norel, Vincent De Montpreville, Marie-Christine Guillet, Icilio Cavero, Charles Brink

Journal:

British Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.04 MB

english, 1995

42

Endothelin - a new family of endothelium-derived peptides with widespread biological properties

Anne-Charlotte Le Monnier de Gouville, Howard L. Lippton, Icilio Cavero, Warren R. Summer, Albert L. Hyman

Journal:

Year:

1989

Language:

english

File:

PDF, 1.27 MB

english, 1989

43

Comparison of Cardiovascular Actions of Dihydralazine, Phentolamine, and Prazosin in Spontaneously Hypertensive Rats

Lefèvre-Borg, Françoise, Roach, Alan G., Cavero, Icilio

Journal:

Journal of Cardiovascular Pharmacology

Year:

1979

File:

PDF, 530 KB

1979

44

Mechanism of Antihypertensive Activity of Orally Administered Prazosin in Spontaneously Hypertensive Rats

Lefèvre-Borg, Françoise, Roach, Alan G., Roberto, Gomeni, Cavero, Icilio

Journal:

Journal of Cardiovascular Pharmacology

Year:

1979

File:

PDF, 551 KB

1979

45

19 th Annual Meeting of the Safety Pharmacology Society: regulatory and safety perspectives for advanced therapy medicinal products (cellular and gene therapy products)

Cavero, Icilio, Seimetz, Diane, Koziel, David, Zimmermann, Wolfram-Hubertus, Holzgrefe, Henry H

Journal:

Expert Opinion on Drug Safety

Year:

2020

File:

PDF, 954 KB

2020

46

Synthesis and antihypertensive activity of a series of 4-amino-6,7-dimethoxyquinazoline derivatives

Binet, Jean L., Dumas, Andre P., Lefevre-Borg, Francoise, Cavero, Icilio, Manoury, Philippe M.

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 898 KB

english, 1986

47

Moving towards better predictors of drug-induced Torsade de Pointes

Cavero, Icilio, Crumb, William

Journal:

Expert Opinion on Drug Safety

Year:

2006

Language:

english

File:

PDF, 104 KB

english, 2006

48

Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation

Cavero, Icilio, Guillon, Jean-Michel, Ballet, Veronique, Clements, Mike, Gerbeau, Jean-Frédéric, Holzgrefe, Henry

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2016

Language:

english

File:

PDF, 1.11 MB

english, 2016

49

Rat Juxtaglomerular Cells are Endowed with DA-1 Dopamine Receptors Mediating Renin Release

Kurtz, Armin, Bruna, Roberto Delia, Pratz, Jean, Cavero, Icilio

Journal:

Journal of Cardiovascular Pharmacology

Year:

1988

File:

PDF, 477 KB

1988

50

Frequency-independent blockade of cardiac Na+channels by riluzole: comparison with established anticonvulsants and class I anti-arrhythmics

Michel Mestre, Yasmine Djellas, Thierry Carriot, Icilio Cavero

Journal:

Fundamental & Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 918 KB

english, 2000

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